Transdifferentiation-inducing HCCR-1 oncogene
نویسندگان
چکیده
منابع مشابه
Transcriptional activation of the melanoma inducing Xmrk oncogene in Xiphophorus.
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متن کاملThe HCCR oncoprotein as a biomarker for human breast cancer.
PURPOSE HCCR oncoprotein is reported to be related to tumorigenesis, including breast cancer, functioning as a negative regulator of p53. Mice transgenic for HCCR developed breast cancers. The objective of this study was to validate the HCCR oncoprotein as a candidate biomarker for breast cancer. EXPERIMENTAL DESIGN HCCR expression in breast cancer cells was analyzed by quantitative PCR, ELIS...
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OBJECTIVE This study was to explore the expression of human cervical cancer oncogene-1 (HCCR-1) in colon cancer and its clinical significance. METHODS RT-PCR, immunohistochemistry and Western blot assay were employed to detect HCCR-1 expression in 152 colon cancers, 43 adjacent non-cancerous tissues and 37 normal tissues. In addition, immunohistochemistry was done to detect CEA in colon cance...
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ژورنال
عنوان ژورنال: BMC Cell Biology
سال: 2010
ISSN: 1471-2121
DOI: 10.1186/1471-2121-11-49